In the case of Hoffmann v Court Caribbean Law Practice, the Employment Rights Tribunal confirmed that it is not automatically unfair to dismiss an employee due to their transgender under section 30 of the Employment Rights Act 2012.
Please note that the Employment (Prevention of Discrimination) Act 2020 (E(PD)A) does not apply to transgender discrimination. See section 3(2) of the E(PD)A.
Transgender Discrimination Laws in England
In England, the Sex Discrimination (Gender Reassignment) Regulations 1999 came into force on 1 May 1999. These transgender discrimination laws can now be found in the Equality Act 2010. Also, the Gender Recognition Act 2004 allows a transgender person to obtain legal recognition for their acquired gender - and change the recorded sex on their birth certificate from male to female or vice versa.
Disability Discrimination
See the below comments about the Rights of Persons with Disabilities Bill.